CDC recommends children get two doses of MMR vaccine, starting with the first dose at 12 through 15 months of age, and the second dose at 4 through 6 years of age.

Refer to Tetanus Toxoid in Part 4 for additional information. Pain and redness at the injection site or fever less than 39°C occur in 10% or more of vaccine recipients. Yellow fever vaccine: Recommendations of the Advisory Committee on Immunization Practices (ACIP), 2002.
Use the current Advisory Committee on Immunization Practices (ACIP) immunization schedule to determine what recommended vaccines are needed based on the patient’s immunization history. However, if given between 6 months and less than 12 months of age, 2 additional doses of measles-containing vaccine must be administered after the child is 12 months old (and at least 4 weeks after the previous dose) to ensure long lasting immunity to measles.

J Infect Dis 1999;180:187-90. De Serres G, Sciberras J, Naus M et al. The MMR vaccine is an injection given to help prevent measles, mumps, and rubella. Last vaccine dose must be administered at or after 12 months of age. King A, Varughese P, De Serres G et al.

Refer to vaccine-specific chapters in Part 4 for additional information. March 2019. In the mid to late 1990s, researchers from the United Kingdom reported an association between MMR vaccine and inflammatory bowel disease, and MMR vaccine and autism. Two additional doses of MMR vaccine provided after 12 months of age are required for long-term protection. Refer to measles for health professionals for more information, including disease description, distribution and epidemiology.

Refer to Contraindications, Precautions and Concerns in Part 2 for additional information. There are no data regarding the long-term effectiveness of MMRV vaccine. For more information, refer to Blood Products, Human immunoglobulin and Timing of Immunization in Part 1. Simultaneous administration of hepatitis B and yellow fever vaccines. Taylor B, Miller E, Lingam R et al. Summary of updated measles PEP recommendations for susceptible contacts, Storage and Handling of Immunizing Agents, Canadian Communicable Disease Report (CCDR), Contents of Immunizing Agents Available for Use in Canada, travellers to destinations outside of Canada, students in post-secondary educational settings, Immunization of Persons with Inadequate Immunization Records, Blood products, human immunoglobulin and timing of immunization, Immunization in pregnancy and breastfeeding, Immunization of Patients in Health care Institutions, Immunization of Persons with Chronic Diseases, Immunization of Immunocompromised Persons, Blood Products, Human Immunoglobulin and Timing of Immunization, Blood Products, Human immunoglobulin and Timing of Immunization, guidelines for measles outbreak in Canada, Reporting Adverse Events Following Immunization (AEFI) in Canada, Adverse Events Following Immunization (AEFI), Anaphylactic Hypersensitivity to Egg and Egg-Related Antigens, Immunization in Pregnancy and Breastfeeding, Contraindications, Precautions and Concerns, Blood Products, Human Immunoglobulin and Timing of Immunization, https://professionaleducation.blood.ca/en/transfusion/clinical-guide/immune-globulin-products, Susceptible immunocompetent infants 6-12 months old, Susceptible immunocompetent individuals 12 months and older, Immunocompromised individuals 6 months and older, Individuals with confirmed measles immunity. Refer to Blood Products, Human Immune Globulin and Timing of Immunization in Part 1 for guidelines for the interval between administration of immune globulin preparations or other blood products and measles-mumps-rubella (MMR), measles-mumps-rubella-varicella (MMRV) or univalent varicella vaccine vaccines. Grifols Therapeutics LLC. If serology is inadvertently done subsequent to appropriate measles immunization and does not demonstrate immunity, measles re-immunization is not necessary. Guidelines for control of measles outbreaks in Canada. You will be subject to the destination website's privacy policy when you follow the link. Refer to Timing of Vaccine Administration in Part 1 for additional information about concurrent administration of measles-containing vaccine with other vaccines. 24 weeks

It is recommended to avoid the use of salicylates (medications derived from salicylic acid, such as acetylsalicylic acid [ASA]) for 6 weeks after immunization with MMRV vaccine because of an association between wild-type varicella, salicylate therapy and Reye's syndrome. Refer to Anaphylactic Hypersensitivity to Egg and Egg-Related Antigens in Part 2 for additional information. Adults born before 1970 are generally presumed to have acquired natural immunity to measles; however, some of these individuals may be susceptible. When considering immunization of an immunocompromised person with a live vaccine, approval from the individual's attending physician should be obtained before vaccination. There is no evidence of increased risk of new onset chronic arthropathies. Refer to Haemophilus Influenzae Type B Vaccine in Part 4 for additional information. Each module provides learning opportunities, self-test practice questions, reference and resource materials, and an extensive glossary. Refer to Immunization of Travellers chapter in Part 3 for detailed information about accelerated immunization schedules for travel health protection. Product Monograph - PRIORIX-TETRA™. Significant revisions included in this chapter are highlighted in the Table of updates to the Canadian Immunization Guide. Pediatrics 2001;107:E84.

DeStefano F, Goodman RA, Noble GR et al. For enquiries, contact us. Refer to Vaccine Administration Practices in Part 1 for additional information about administration of multiple injections. Refer to Immunization of Immunocompromised Persons in Part 3 for more information.

Teens and adults should also be up to date on their MMR vaccination. When the first dose of measles-containing vaccine is administered to children 12 to 23 months as MMRV vaccine, there is a higher risk of fever and febrile seizures in the 7 to 10 days after vaccination when compared to separate administration of MMR and varicella vaccine at the same visit. … Tetanus toxoid, reduced diphtheria, reduced acellular pertussis (Tdap). You Call the Shots . Do ensure that the person who drew up the vaccine administers it. Centers for Disease Control and Prevention.

Persons with a minor acute illness, with or without fever, may be vaccinated. Rarely, Immune Thrombocytopenic Purpura (ITP) occurs within 6 weeks after immunization with MMR or MMRV vaccine. Protection after two doses of measles vaccine is independent of interval between doses. Elk Grove Village, IL: American Academy of Pediatrics; 2012. Measles-susceptible adolescents (refer to Table 1 for criteria for immunity) should receive 2 doses of MMR vaccine, given at least 4 weeks apart.

Statement on measles-mumps-rubella-varicella vaccine. Typhoid immunization: recommendations of the Advisory Committee on Immunization Practices (ACIP). Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. People who recover from measles have permanent immunity to the disease. Symptoms of measles include prodromal fever, cough, coryza, conjunctivitis, Koplik spots (white spots on the inner lining of the mouth) and a rash that typically begins on the face, advances to the trunk and then to the arms and legs. Refer to Immunization of Patients in Health care Institutions in Part 3 for additional information.

Refer to.
Measles during pregnancy results in a higher risk of premature labour, spontaneous abortion and low birth weight infants. Serious adverse events are rare following immunization and, in most cases, data are insufficient to determine a causal association. Journal of Medical Virology 1986;19(4):307-11. Long-term protection against measles is only provided following immunization with MMR vaccine. The incubation period is about 10 days (range, 7 to 18 days). They may be more likely to experience more severe disease and complications.

Administration of MMR or MMRV vaccine should be postponed in persons with severe acute illness. CDC recommends that all health care personnel who administer vaccines receive comprehensive, competency-based training on vaccine administration policies and procedures BEFORE administering vaccines. J Infect Dis 2005;192(10):1686-93. National Advisory Committee on Immunization. Prior egg ingestion is not a prerequisite for immunization with egg protein-containing vaccine. If there is a requirement for both vaccines, the varicella-containing vaccine should be administered at least 4 weeks before or after smallpox vaccine. MMR or MMRV vaccine can be administered in the routine manner to people who have a history of anaphylactic hypersensitivity to hens' eggs. Two doses of measles-containing vaccine are still required after the first birthday for long-term protection. Refer to Contents of Immunizing Agents Available for Use in Canada in Part 1 for lists of vaccines and passive immunizing agents available in Canada and their contents. General recommendations on immunization: recommendations of the Advisory Committee on Immunization Practices (ACIP).

Human papillomavirus nine-valent (HPV9), 4 weeks (3 dose schedule) For susceptible individuals who are pregnant or immunocompromised, IMIg can be provided at a dose of 0.5mL/kg understanding that those weighing 30 kg or more will not receive the measles antibody concentrations that are considered to be fully protective. Re-immunization with measles-containing vaccine after age and risk appropriate vaccination is not necessary.

Measles occurs worldwide and is one of the most highly communicable diseases. MMWR Morb Mortal Wkly Rep 2008;57:258-60. In these cases, the dose of the second vaccine is considered invalid and should be repeated after the recommended interval. The Pink Book: Epidemiology and Prevention of Vaccine Preventable Diseases. Proper vaccine administration is critical to ensure that vaccination is safe and effective. When two live parenteral vaccines are given less than 4 weeks apart, the immune response to the second vaccine may be diminished by the immune response to the first vaccine. Pregnant women who are susceptible to measles should have vaccination offered post-partum. Measles-susceptible adults (refer to Table 1 for criteria for immunity) should receive 1 or 2 doses of MMR vaccine as appropriate for age and risk factors. Protection against measles is especially important for people planning travel. JAMA 1982; 247(18):2551-54. For all vaccines, immunization should always be performed by personnel with the capability and facilities to manage adverse events post-vaccination. Refer to vaccine-specific chapters in Part 4 for additional information on recommended and minimum dose intervals for vaccine administration. A 2 dose schedule may be used for adolescents 9 to less than 15 years of age. MMR and MMRV vaccines and Ig are contraindicated in persons with a history of anaphylaxis after previous administration of the product and in persons with proven immediate or anaphylactic hypersensitivity to any component of the product, with the exception of egg allergy for MMR and MMRV vaccines. Varicella that is moderate (50 to 500 lesions) or severe (more than 500 vesicular lesions or associated complications or hospital admission) and occurs within 7 to 21 days after vaccination with MMRV vaccine.


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